Fig. 3.

Poly-ICR induces HPV16-exposed LC to produce high levels of inflammatory cytokines and chemokines. LC were exposed to HPV16 prior to treatment with s-Poly-I:C (Poly-ICR) (N=7 individual donors). Cell supernatants were analyzed for a panel of ten cytokines and chemokines using a Bio-Plex Suspension Array System. Data represent the mean (±SEM) analyte concentration. ^⁎p<0.05, ^⁎⁎p<0.01, ^⁎⁎⁎p<0.001, ^⁎⁎⁎⁎p<0.0001 compared to untreated LC and LC exposed to HPV16 (one-way ANOVA, Tukey׳s post-test).