Table 1. Expression of Select Genes Related to Inflammation, Longevity and Cognition when examined a day after status epilepticus (SE).
| Gene | Naïve Control | SE-VEH | SE-RESV | ANOVA |
|---|---|---|---|---|
| Mean ± S.E.M | Mean ± S.E.M | Mean ± S.E.M | p-value | |
| IL1β | 0.000220 ± 0.00002 | 0.000313 ± 0.000047 | 0.0002425 ± 0.000019 | p > 0.05 |
| TNF-α | 0.000203 ± 0.00007 | 0.00070 ± 0.000038 | 0.00058 ± 0.000046 | p < 0.0001 |
| (Naive vs SE-VEH, p < 0.001; Naive vs SE-RESV, p < 0.001, SE-VEH vs SE-RESV, p > 0.05) | ||||
| NF-kB | 0.00476 ± 0.00098 | 0.009995 ± 0.0011 | 0.007802 ± 0.00162 | p > 0.05 |
| IFN-γ | 0.00002 ± 0.000002 | 0.000014 ± 0.000002 | 0.0000115 ± 0.0000007 | p > 0.05 |
| IL4 | 0.000084 ± 0.000009 | 0.00017 ± 0.0000077 | 0.00018 ± 0.000034 | p > 0.05 |
| IL10 | 0.003974 ± 0.001234 | 0.00263 ± 0.000555 | 0.00360 ± 0.00048 | p > 0.05 |
| MPO | 0.000035 ± 0.000009 | 0.000121 ± 0.000039 | 0.000085 ± 0.0000145 | p > 0.05 |
| SIRT1 | 0.00745 ± 0.0007 | 0.008357 ± 0.0007 | 0.008581 ± 0.00071 | p > 0.05 |
| FOXO3 | 0.01386 ± 0.0018 | 0.01015 ± 0.0008 | 0.01125 ± 0.00072 | p > 0.05 |
The numbers depict 2^delta Ct values. IL1β, interleukin 1-beta; TNF-α, tumor necrosis factor-alpha; NF-kB, nuclear factor of kappa light polypeptide gene enhancer in B-cells; IFN-γ, interferon-gamma; MPO, myeloperoxidase; IL4, interleukin 4; IL10, interleukin 10; SIRT1, sirtuin 1; FOXO3, forkhead box O3.