Table 1. miR-29 family and cerebral ischemia.
| miR-29 | Species | Type of ischemia | Change of miR-29 | Detection method | Targets | Treatment | References |
|---|---|---|---|---|---|---|---|
| a, b, c | Rat | Focal | Decrease in brain | Microarray | N/D | N/D | Jeyaseelan et al29 |
| b, c | Rat | Focal | Decrease in brain | Microarray | N/D | N/D | Dharap et al11 |
| b, c | Human | Young Stroke | Increase in blood | Microarray | N/D | N/D | Tan et al31 |
| a, b, c | Rat | Global | Increase in Hippocampus | Microarray | N/D | N/D | Yuan et al30 |
| b | Rat | Focal | Increase in brain | RT-qPCR | BCL2L2 | N/D | Shi et al33 |
| a | Rat | Global | Decrease in hippo. CA1, increase in hippo. DG | RT-qPCR | BBC3 | Overexpress miR-29a in CA1 | Ouyang et al8, 32 |
| b | Mouse | Focal | Decrease in brain | RT-qPCR | N/D | Overexpress | Khanna et al13 |
| c | Mouse | Focal | Decrease in brain | RT-qPCR | DNMT3a | Overexpress | Pandi et al43 |
| b | Human Mouse | Old stroke, Stroke | Decrease in blood and brain | RT-qPCR | AQP4 | Overexpress | This study |
AQP4, aquaporin 4; BBC3, BCL2 binding component 3; DG, dentate gyrus; DNMT3a, DNA methyltransferase 3a; miR-29a, microRNA-29a; N/D, no information about the target genes of miR29.