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. 2015 Dec 7;7:126. doi: 10.1186/s13073-015-0250-3

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© Hunt et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Linkage disequilibrium across the two associated regions. Mountain plots generated by Haploview [38] for (a) rs9939609:T > A associated region chr16:53,797,908-53,846,168 (48.3 kb) and (b) the novel associated region at chr16:54,812,014-54,865,446 (53.4 kb), across our complete study group. Bright red represents D’ = 1 and LOD ≥ 2 (complete dependence and strong evidence for linkage); shades of pink/red represent D’ < 1 and LOD ≥ 2; blue represents D’ = 1 and LOD < 2; white represents D’ < 1 and LOD < 2(low dependency and poor evidence for linkage). The full plot of the region sequenced is shown for reference (chr16:53500000-55500000)