Table 4.
Group mean difference in ln-blood As decline since baseline estimated from repeated measures model.a
| Time period | Group comparison | Group mean difference in ln-bAs decline from baseline (95% CI) | p-Value |
|---|---|---|---|
| Week 1–12 | FA800 vs. placebo | –0.09 (–0.18, –0.01) | 0.03 |
| Week 13–24 | FA800/placebo vs. placebo | –0.14 (–0.26, –0.02) | 0.02 |
| FA800/FA vs. placebo | –0.12 (–0.24, –0.00) | 0.04 | |
| FA800/FA vs. FA800/placebo | 0.02 (–0.09, 0.12) | 0.72 | |
| aThe model parameters: six for the time trend in the placebo group, one for the difference between FA800 and placebo groups, and three for the time by treatment group interactions to describe the differences in the time trend between the FA800 group(s) and the placebo group. No other covariates were adjusted for in this model. | |||