Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Difference in the binding of the inhibitors 594 and FID in the structure FID>594. Inhibitor FID (magenta) binds only to the active site while 594 (violet) binds both to the active site and to the specificity pocket (marked S). Residues Phe 122, Leu 130, and Leu 300 in the conformation that binds 594 are shown in cyan, and residue Leu 300 in the conformation that binds FID is shown in magenta. The cartoon representation of the fold in the conformation that binds 594 is shown in green.
