Table 2.

Prospective studies of ketogenic diets in oncology

Trial	Carbohydrate Restriction	Timeline of Assessment	Tolerability (% on diet)	Weight Loss (mean, kg)	Response
Schmidt et al54	70 g/day	3 months	31% (of 16)	2 kg	5 SD, 6 PD, 4 Unknown
Fine et al53 (RECHARGE)	CHO restriction to 5% of total energy	1 month	50% (of 10)	3 kg	5 SD, 1 PR, 4 PD
Rieger et al55 (ERGO)	60 g/day	∼5 weeks	85% (of 20)	2.2% loss	Median OS 32 weeks

Abbreviations: CHO, carbohydrate; g, grams; OS, overall survival; PD, progressive disease; PR, partial response; SD, Stable disease.