Table 3.
Demographic, oncologic, and epileptic characteristics
Patient | Sex | Age at Diet Initiation (years) | Carb Limit (grams/day) | Tumor Type | Tumor Location | Prior Tumor Treatment | Active Chemo During MAD | Seizure Type | Prior AED (no.) | Active AEDs at Initiation |
---|---|---|---|---|---|---|---|---|---|---|
1 | Male | 30 | 20 | AA | L parietal | Sx, XRT, TMZ | None | CPS | 1 | LEV |
2 | Female | 54 | 20 | Sec GBM | L parietal | Sx, XRT, TMZ | TMZ, Bev | CPS | 5 | LEV, PHT, LMT, KLO |
3 | Male | 48 | 20 | LGO | L frontal | Sx | None | SPS, CPS | 3 | LEV |
4 | Male | 37 | 15 | Rec GBM | L temporal | Sx, XRT, TMZ, Bev, ICT-107, Veliparib | Bev, LBH589 | GTC | 1 | LEV |
5 | Female | 38 | 20 | LGO | L temporal | Sx | None | GTC | 1 | None |
6 | Male | 28 | 20 | LGO | L temporal | Sx, TMZ | TMZ | GTC, SPS | 6 | PHT, TPM |
7 | Female | 54 | 20 | LGA | L parietal | Sx, XRT, TMZ | None | CPS, GTC | 1 | LEV |
8 | Female | 43 | 20 | GBM | L frontal | Sx, XRT, TMZ | None | CPS, GTC | 5 | LCM, VPA, LEV |
Abbreviations: AA, anaplastic astrocytoma; AED, antiepileptic drug; BEV, bevacizumab; CPS, complex partial seizures; CZ, clonazepam; GBM, glioblastoma multiforme; GTC, generalized tonic-clinic seizures); LCM, lacosamide; LEV, levetiracetam; LGA, low-grade astrocytoma; LGO, low-grade oligodendroglioma; LMT, lamictal; no., number; PHT, phenytoin; SPS, simple partial seizures; Sx, surgery; TMZ, temozolomide; TPM, topamax; VPA, valproic acid; XRT, radiation therapy.