Table 1.
Baseline characteristics according to BNP (pg/mL) quartiles.
| Variable | Total cohort a | Q1 (n = 57) | Q2 (n = 59) | Q3 (n = 57) | Q4 (n = 58) | p-Value |
|---|---|---|---|---|---|---|
| Age, yearb | 72.5 ± 13.1 | 65.6 ± 12.4 | 71.7 ± 13.5 | 74.1 ± 13.1 | 78.7 ± 9.8 | <0.001 |
| Male gender, % (n) | 61.9 (143) | 64.9 (37) | 67.8 (40) | 54.4 (31) | 60.3 (35) | 0.473 |
| Risk markers at baseline | ||||||
| Peak TnT (ng/mL)c | 0.04 (0.02–0.06) | 0.04 (0.03–0.07) | 0.04 (0.02–0.07) | 0.04 (0.02–0.06) | 0.04 (0.03–0.06) | 0.599 |
| hsCRP (mg/L)c | 6.3 (1.9–20.0) | 3.4 (1.6–12.7) | 3.5 (1.6–17.0) | 7.8 (2.1–20.5) | 9.2 (3.2–30.3) | 0.016 |
| BNP (pg/mL)c | 193 (66–442) | 35 (22–55) | 117 (88–157) | 295 (241–365) | 707 (570–1196) | <0.001 |
| Risk factors | ||||||
| Current smoking, % (n) | 15.6 (36) | 26.3 (15) | 8.5 (5) | 14.0 (8) | 13.8 (8) | 0.058 |
| Hypertension, % (n) | 57.1 (132) | 52.6 (30) | 55.9 (33) | 59.7 (34) | 60.3 (35) | 0.826 |
| IDDM, % (n) | 1.3 (3) | 1.8 (1) | 0 (0) | 3.5 (2) | 0 (0) | 0.283 |
| NIDDM, % (n) | 30.3 (70) | 24.6 (14) | 30.5 (18) | 40.4 (23) | 25.9 (15) | 0.245 |
| eGFR (mL/min/1.73m2)b | 61.2 ± 28.8 | 76.1 ± 20.9 | 62.0 ± 31.6 | 57.3 ± 29.5 | 49.4 ± 25.7 | <0.001 |
| Hypercholesterolemia, % (n) | 36.4 (84) | 38.6 (22) | 35.6 (21) | 36.8 (21) | 34.5 (20) | 0.972 |
| History of CHD | ||||||
| Angina pectoris, % (n) | 42.0 (97) | 36.8 (21) | 39.0 (23) | 45.6 (26) | 46.6 (27) | 0.650 |
| MI, % (n) | 28.1 (65) | 10.5 (6) | 25.4 (15) | 42.1 (24) | 34.5 (20) | 0.001 |
| CABG, % (n) | 10.8 (25) | 3.5 (2) | 11.9 (7) | 12.3 (7) | 15.5 (9) | 0.197 |
| PCI, % (n) | 10.8 (25) | 10.5 (6) | 11.9 (7) | 10.5 (6) | 10.3 (6) | 0.993 |
| History of heart failure | ||||||
| CHF, % (n) | 34.2 (79) | 19.3 (11) | 27.1 (16) | 38.6 (22) | 51.7 (30) | 0.002 |
| Known CHD, % (n) | 61.9 (143) | 49.1 (28) | 55.9 (33) | 68.4 (39) | 74.1 (43) | 0.023 |
| Treatment prior to admission | ||||||
| Beta blockers, % (n) | 33.8 (78) | 24.6 (14) | 33.9 (20) | 38.6 (22) | 37.9 (22) | 0.361 |
| Index diagnosis | ||||||
| STEMI, % (n) | 7.4 (17) | 10.7 (6) | 6.8 (4) | 10.5 (6) | 1.7 (1) | 0.214 |
| Country | ||||||
| Argentina, % (n) | 47.2 (109) | 57.9 (33) | 61.0 (36) | 42.1 (24) | 27.6 (16) | 0.001 |
aTotal cohort with available measurements: TnT; n = 230, hsCRP; n = 238, BNP; n = 231.
bAge, eGFR, total cholesterol, HDL cholesterol, and triglycerides are given as mean ± SD.
cPeak TnT, hsCRP, and BNP are given as median (quartiles Q1–Q3).
TnT, troponin-T; hsCRP, high-sensitive C-reactive protein; BNP, B-type natriuretic peptide; IDDM, insulin-dependent diabetes mellitus; NIDDM, non-insulin-dependent diabetes mellitus; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; CABG, coronary artery bypass graft; PCI, percutaneous coronary intervention; CHF, congestive heart failure; CHD, coronary heart disease; STEMI, ST-segment elevation myocardial infarction.