Table 2.
Baseline characteristics according to hsCRP (mg/L) quartiles.
| Variable | Total cohort a | Q1 (n = 58) | Q2 (n = 61) | Q3 (n = 59) | Q4 (n = 60) | p-Value |
|---|---|---|---|---|---|---|
| Age, yearb | 72.7 ± 13.0 | 70.6 ± 13.8 | 71.2 ± 11.1 | 75.3 ± 13.4 | 73.7 ± 13.2 | 0.171 |
| Male gender, % (n) | 62.2 (148) | 63.8 (37) | 62.3 (38) | 64.4 (38) | 58.3 (35) | 0.904 |
| Risk markers at baseline | ||||||
| Peak TnT (ng/mL)c | 0.04 (0.02–0.06) | 0.05 (0.03–0.07) | 0.04 (0.03–0.06) | 0.04 (0.02–0.06) | 0.04 (0.02–0.06) | 0.256 |
| hsCRP (mg/L)c | 6.35 (1.90–20.0) | 1.2 (0.5–1.6) | 3.1 (2.4–4.6) | 11.2 (8.3–16.0) | 46.2 (29.8–132.8) | <0.001 |
| BNP (pg/mL)c | 193 (65–443) | 100 (51–283) | 172 (64–372) | 231 (72–473) | 276 (104–567) | 0.006 |
| Risk factors | ||||||
| Current smoking, % (n) | 15.5 (37) | 12.1 (7) | 16.4 (10) | 10.2 (6) | 23.3 (14) | 0.200 |
| Hypertension, % (n) | 56.3 (134) | 56.9 (33) | 57.4 (35) | 52.5 (31) | 58.3 (35) | 0.924 |
| IDDM, % (n) | 1.3 (3) | 1.7 (1) | 0 (0) | 1.7 (1) | 1.7 (1) | 0.790 |
| NIDDM, % (n) | 29.8 (71) | 24.1 (14) | 31.2 (19) | 33.9 (20) | 30.0 (18) | 0.702 |
| eGFR (mL/min/1.73m2)b | 61.3 ± 28.5 | 67.7 ± 27.9 | 64.4 ± 25.2 | 60.9 ± 27.6 | 52.3 ± 31.2 | 0.020 |
| Hypercholesterolemia, % (n) | 35.7 (85) | 48.3 (28) | 42.6 (26) | 27.1 (16) | 25.0 (15) | 0.017 |
| History of CHD | ||||||
| Angina pectoris, % (n) | 42.4 (101) | 39.7 (23) | 49.2 (30) | 49.2 (29) | 31.7 (19) | 0.154 |
| MI, % (n) | 28.2 (67) | 25.9 (15) | 31.1 (19) | 32.2 (19) | 23.3 (14) | 0.662 |
| CABG, % (n) | 10.9 (26) | 10.3 (6) | 16.4 (10) | 5.1 (3) | 11.7 (7) | 0.262 |
| PCI, % (n) angina | 10.1 (24) | 15.5 (9) | 18.0 (11) | 0 (0) | 6.7 (4) | 0.004 |
| History of heart failure | ||||||
| CHF, % (n) | 35.3 (84) | 25.9 (15) | 27.9 (17) | 44.1 (26) | 43.3 (26) | 0.060 |
| Known CHD, % (n) | 62.6 (149) | 58.6 (34) | 67.2 (41) | 66.1 (39) | 58.3 (35) | 0.632 |
| Treatment prior to admission | ||||||
| Beta blockers, % (n) | 33.6 (80) | 37.9 (22) | 45.9 (28) | 30.5 (18) | 20.0 (12) | 0.020 |
| Index diagnosis | ||||||
| STEMI, % (n) | 7.2 (17) | 6.9 (4) | 13.3 (8) | 3.4 (2) | 5.0 (3) | 0.163 |
| Country | ||||||
| Argentina, % (n) | 45.4 (108) | 50.0 (29) | 47.5 (29) | 37.3 (22) | 46.7 (28) | 0.529 |
aTotal cohort with available measurements: TnT; n = 230, hsCRP; n = 238, BNP; n = 231.
bAge, eGFR, total cholesterol, HDL cholesterol, and triglycerides are given as mean ± SD.
cPeak TnT, hsCRP, and BNP are given as median (quartiles Q1–Q3).
TnT, troponin-T; HsCRP, high-sensitive C-reactive protein; BNP, B-type natriuretic peptide; IDDM, insulin-dependent diabetes mellitus; NIDDM, non-insulin-dependent diabetes mellitus; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; CABG, coronary artery bypass graft; PCI, percutaneous coronary intervention; CHF, congestive heart failure; CHD, coronary heart disease; STEMI, ST-segment elevation myocardial infarction.