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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Endocr Relat Cancer. 2015 Nov 9;23(1):53–63. doi: 10.1530/ERC-15-0417

Figure 4. The effects of S3I-201 on protein levels of regulators in the STAT3 pathway in thyroids of HFD-wild type and HFD- ThrbPV/PVPten+/− mice.

Figure 4

(A) Western blot analysis of protein abundance of leptin receptor, phosphorylated -JAK2 (Y1007/1008), total JAK-2, phosphorylated STAT3 (Y705), total-STAT3, and GAPDH as a loading control after treatment with vehicle or S3I-201 in wild type (n=2) and ThrbPV/PVPten+/− mice (n=2). (B) The band intensities of the protein detected in (A) were quantified and compared. The data, shown as mean ± SE, were analyzed by Student’s t test.