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. Author manuscript; available in PMC: 2015 Dec 7.
Published in final edited form as: J Nat Prod. 2011 May 3;74(5):1015–1020. doi: 10.1021/np100918z

Table 2.

Pdcd4-Stabilizing Activity of Compounds 1–8

compound Pdcd4 EC50a (µM)
1 4.9
2 3.0
3 1.6
4 1.5
5 1.8
6 3.5
7 1.3
8 1.8
rapamycinb 0.05
a

EC50 values represent the minimum concentration required for 50% recovery of the Pdcd4-luciferase signal from TPA-induced degradation.

b

Positive control.