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Newer material jetting 3D printing technologies and materials allow direct printing of a compliant vessel wall (2–3 mm thickness) with sufficient tensile strength to be used for realistic flow physiology experiments. In the CT angiographic experiment shown, a pulsatile flow pump and ultrasonic flowmeter (green inset a) are attached to a coronary phantom (red inset b) that was fabricated by segmentation of a patient’s contrast-enhanced coronary CT angiograms.