Table 2. Cardiometabolic biomarker values in 18- to 20-year-old African Americans with and without prenatal cocaine exposure (n=350).
| Prenatal Cocaine Exposure | ||||
| Dependent Measure | SR-/BE- n = 171 | SR+/BE- n = 25 | SR-/BE+ n = 59 | SR+/BE+ n = 95 |
| Insulin, mean (SD), uIU/mLa | 10.1 (6.3) | 9.6 (6.4) | 9.7 (7.3) | 10.4 (6.3) |
| Glucose, mean (SD), mg/dL | 88.9 (9.2) | 89.3 (6.3) | 90.6 (8.5) | 90.4 (12.5) |
| Triglycerides, mean (SD), mg/dLa | 58.5 (18.6) | 60.3 (18.2) | 60.2 (22.6) | 63.0 (22.8) |
| HDL cholesterol, mean (SD), mg/dL | 51.8 (12.8) | 53.7 (14.6) | 51.5 (14.1) | 49.0 (11.3) |
| LDL cholesterol, mean (SD), mg/dL | 87.0 (26.5) | 88.4 (25.9) | 85.1 (25.7) | 84.7 (27.2) |
| VLDL cholesterol, mean (SD), mg/dL | 12.6 (5.4) | 13.7 (8.8) | 13.1 (6.5) | 13.6 (5.6) |
| Non-HDL cholesterol, mean (SD), mg/dL | 99.6 (27.4) | 102.2 (25.9) | 98.2 (28.6) | 98.3 (28.7) |
| Total cholesterol, mean (SD), mg/dL | 151.4 (28.5) | 155.9 (28.4) | 149.7 (29.8) | 147.4 (29.4) |
| Hs-CRP, mean (SD), mg/dLa | 0.94 (1.6) | 0.82 (1.8) | 1.19 (2.5) | 0.93 (2.2) |
| Systolic blood pressure, mean (SD), mm Hg | 111.5 (10.3) | 107.4 (8.9) | 111.0 (10.1) | 111.0 (10.6) |
| Diastolic blood pressure, mean (SD), mm Hg | 69.5 (7.2) | 66.1 (5.5) | 69.2 (7.5) | 69.4 (7.6) |
| Metabolic syndrome Ib, % | 1.2 | 4.0 | 5.1 | 3.2 |
| Metabolic syndrome IIc, % | 15.8 | 16.0 | 20.3 | 19.0 |
SR+/-, self-report positive/negative prenatal cocaine use; BE+/-, benzoylecgonine positive/negative prenatal presence; HDL, high density lipoprotein; LDL, low density lipoprotein; VLDL, very low density lipoprotein except for metabolic syndrome (externally corrected for sex), means are corrected for sex and age in the statistical model. Standard deviations are uncorrected.
a. Values were loge transformed to normalize the distributions before analysis. Table values have been transformed back to the original scale. Standard deviations were estimated from the 17th and 83rd smoothed empirical likelihood quantiles of the log-normalized distribution.
b. Standard Adult Treatment Panel III definition ( ≥3 risk factors).
c. Modified Adult Treatment Panel III definition ( ≥2 risk factors).