Table 1. PPARα L162V, PPARγ2 C161T and PPARδ T294C allele distribution according to demographic and anthropometric-clinical classes.
Alleles | Ethnicity | Sex | Obesity | Met-S | Obese with Met-S | ||||||
Malay n (%) | Chinese n (%) | Indian n (%) | Male n (%) | Female n (%) | Non-obese n (%) | Obese n (%) | Absent n (%) | Present n (%) | Absent n (%) | Present n (%) | |
PPARαL162V | |||||||||||
L162 | 181 (93.3) | 284 (91.6) | 101 (91.8) | 225 (9.7) | 341 (93.2) | 234 (92.1) | 332 (92.2) | 105 (9.5) | 461 (92.6) | 32 (94.1) | 300 (92.0) |
V162 | 13 (6.7) | 26 (8.4) | 9 (8.2) | 23 (9.3) | 25 (6.8) | 20 (7.9) | 28 (7.8) | 11 (9.5) | 37 (7.4) | 2 (5.9) | 26 (8.0) |
χ2; P | .50; .78 | 1.23; .27 | .002; .964 | .550; .458 | NP | ||||||
PPARγ C161T | |||||||||||
C161 | 154 (79.4) | 226 (72.9) | 96 (87.3) | 186 (75.0) | 290 (79.2) | 193 (76.0) | 283 (78.6) | 84 (72.4) | 392 (78.7) | 25 (73.5) | 258 (79.1) |
T161 | 40 (2.6) | 84 (27.1) | 14 (12.7) | 62 (25.0) | 76 (2.8) | 61 (24.0) | 77 (21.4) | 32 (27.6) | 106 (21.3) | 9 (26.5) | 68 (2.9) |
χ2; P | 1.18; .01a | 1.52; .22 | .590; .443 | 2.144; .143 | .577; .448 | ||||||
PPARδ T294C | |||||||||||
T294 | 133 (68.6) | 212 (68.4) | 86 (78.2) | 166 (66.9) | 265 (72.4) | 174 (68.5) | 257 (71.4) | 80 (69.0) | 351 (7.5) | 23 (67.6) | 234 (71.8) |
C294 | 61 (31.4) | 98 (31.6) | 24 (21.8) | 82 (33.1) | 101 (27.6) | 80 (31.5) | 103 (28.6) | 36 (31.0) | 147 (29.5) | 11 (32.4) | 92 (28.2) |
χ2; P | 4.09; .13 | 2.11; .15 | .592; .441 | .103; .748 | .257; .612 |
NP, χ2 test not performed due presence of cell having the count of less than 5, χ2 and P by Pearson’s χ2 test.
a. P significant at <.05.