Table 2. Logistic regression analysis for the association of PPARα L162V, PPARγ2 C161T and PPARδ T294C genotypes/alleles with anthropometric-clinical classesa.
Genotypes and allele | Obesity | Met-S | Obese with Met-S | ||||||
OR | Pb | 95% CI | OR | Pb | 95% CI | OR | Pb | 95% CI | |
PPARα L162V | |||||||||
L162V | .977 | .942 | .519, 1.838 | .944 | .897 | .396, 2.250 | 1.732 | .507 | .342, 8.774 |
V162 | 1.021 | .945 | . 559, 1.867 | .950 | .903 | .417, 2.163 | 1.647 | .530 | .348, 7.804 |
PPARγ2 C161T | |||||||||
C161T/T161T | .783 | .303 | .491, 1.248 | .625 | .165 | .322, 1.214 | .775 | .638 | .269, 2.239 |
T161 | .845 | .391 | .574, 1.243 | .693 | .178 | .407, 1.182 | .764 | .534 | .327 , 1.785 |
PPARδ T294C | |||||||||
T294C/C294C | .714 | .155 | .448, 1.136 | 1.109 | .761 | .571, 2.153 | 1.120 | .834 | .387, 3.244 |
C294 | .850 | .369 | .596, 1.211 | 1.008 | .976 | .607, 1.672 | .910 | .816 | .409, 2.022 |
OR, odds ratio; CI, confidence interval.
a. The wild-type genotypes and alleles were set as reference or OR 1.0. Genotypes for PPARγ2 and PPARδ were combined for analysis.
b.Adjusted for age, sex and ethnicity.