Table 3. Means of anthropometric and clinical measurements according PPARα L162V, PPARγ2 C161T and PPARδ T294C allelesa.
Variables | PPARα L162V | PPARγ2 C161T | PPARδ T294C | ||||||
L162 M:F = 1:.66 Mean age = 53.40 ± 14.00 | V162 M:F = 1:.92 Mean age = 52.08 ± 15.89 | P | C161 M:F = 1:.64 Mean age = 53.38 ± 14.02 | T161 M:F = 1:.82 Mean age = 53.03 ± 14.64 | P | T294 M:F = 1:.63 Mean age = 53.70 ± 14.16 | C294 M:F = 1:.81 Mean age = 52.36 ± 14.14 | P | |
Weighta, kg | 67.33 ± .60 | 68.07 ± 2.05 | .796 | 67.67 ± .65 | 66.38 ± 1.21 | .363 | 67.32 ± .68 | 67.54 ± 1.05 | .781 |
BMIa, kg/m2 | 26.87 ± .23 | 26.86 ± .80 | .890 | 27.03 ± .25 | 26.31 ± .47 | .207 | 26.95 ± .27 | 26.66 ± .41 | .540 |
WC, cm | 91.88 ± .53 | 91.65 ± 1.83 | .903 | 92.00 ± .58 | 91.37 ± 1.08 | .606 | 91.76 ± .61 | 92.09 ± .94 | .769 |
WHRa | .91 ± .01 | .90 ± .02 | .362 | .91 ± .01 | .92 ± .01 | .448 | .91 ± .01 | .91 ± .01 | .954 |
TBFa, % | 33.07 ± .31 | 32.54 ± 1.05 | .815 | 33.26 ± .33 | 32.23 ± .62 | .194 | 33.23 ± .35 | 32.56 ± .54 | .546 |
SF, % | 27.27 ± .36 | 25.70 ± 1.23 | .221 | 27.46 ± .39 | 26.06 ± .73 | .091 | 27.48 ± .41 | 26.38 ± .63 | .146 |
VFLa, % | 12.05 ± .27 | 12.03 ± .94 | .962 | 12.16 ± .30 | 11.66 ± .55 | .396 | 12.10 ± .31 | 11.92 ± .48 | .691 |
RMa, kcal | 1416.70 ± 1.06 | 145.34 ± 34.57 | .355 | 1422.78 ± 1.98 | 1407.45 ± 2.40 | .493 | 1416.41 ± 11.55 | 1426.21 ± 17.74 | .658 |
SMa, % | 24.82 ± .17 | 25.25 ± .59 | .394 | 24.82 ± .19 | 24.96 ± .35 | .630 | 24.72 ± .20 | 25.17 ± .30 | .171 |
SBPa, mm Hg | 14.82 ± .87 | 139.45 ± 2.97 | .589 | 141.34 ± .94 | 138.56 ± 1.75 | .198 | 14.92 ± .99 | 14.22 ± 1.52 | .811 |
DBP, mm Hg | 81.41 ± .52 | 82.13 ± 1.80 | .703 | 81.69 ± .57 | 8.72 ± 1.06 | .424 | 81.66 ± .60 | 81.03 ± .92 | .567 |
FBG a, mg/dL | 7.73 ± .14 | 7.10 ± .50 | .318 | 7.74 ± .15 | 7.49 ± .28 | .267 | 7.76 ± .16 | 7.52 ± .25 | .597 |
FI a, μIU/mL | 12.65 ± .66 | 13.63 ± 2.31 | .627 | 13.17 ± .72 | 11.09 ± 1.35 | .088 | 13.17 ± .75 | 11.61 ± 1.18 | .700 |
HOMA-IRa | 4.55 ± .28 | 4.33 ± .98 | .997 | 4.75 ± .30 | 3.74 ± .57 | .042b | 4.73 ± .32 | 4.04 ± .50 | .487 |
TC, mmol/L | 4.44 ± .04 | 4.21 ± .15 | .139 | 4.42 ± .045 | 4.42 ± .08 | .954 | 4.42 ± .05 | 4.41 ± .07 | .889 |
TG a, mmol/L | 1.49 ± .05 | 1.46 ± .17 | .646 | 1.47 ± .05 | 1.53 ± .10 | .900 | 1.51 ± .06 | 1.43 ± .09 | .845 |
HDL-C a, mmol/L | 1.21 ± .01 | 1.21 ± .05 | .445 | 1.20 ± .01 | 1.25 ± .03 | .223 | 1.22 ± .01 | 1.19 ± .02 | .168 |
LDL-C, mmol/L | 2.55 ± .03 | 2.35 ± .12 | .107 | 2.55 ± .04 | 2.49 ± .07 | .420 | 2.52 ± .04 | 2.58 ± .06 | .430 |
TC/HDL-C ratioa | 3.76 ± .04 | 3.66 ± .14 | .429 | 3.78 ± .04 | 3.69 ± .08 | .297 | 3.73 ± .04 | 3.83 ± .07 | .228 |
Plasma Adiponectina, ng/mL | 6326.88 ± 216.39 | 524.79 ± 761.52 | .120 | 614.54 ± 235.79 | 6618.95 ± 445.36 | .342 | 6319.63 ± 247.68 | 6064.10 ± 387.83 | .458 |
Plasma IL-6a, pg/mL | 8.90 ± .78 | 1.59 ± 2.75 | .041b | 9.13 ± .85 | 8.64 ± 1.61 | .615 | 9.78 ± .89 | 7.18 ± 1.39 | .254 |
BMI, body mass index; WC, waist circumference; WHR, waist-hip ratio; TBF, total body fat; SF, subcutaneous fat; VFL, visceral fat level; RM, resting metabolism; SM, skeletal muscles; SBP, systolic blood pressure: DBP, diastolic blood pressure; FBG, fasting blood glucose; FI, fasting insulin; HOMA-IR, homeostasis model assessment-estimated insulin resistance; TC, total cholesterol; TG, triglycerides; HDL-C, high density lipoprotein-cholesterol; LDL-C, low density lipoprotein-cholesterol; IL-6, Interleukin-6.
a. Values were log transformed before analysis; values are presented as adjusted mean ± SEM (estimated marginal means ± standard error of the mean) by univariate analysis of variance (General Linear Model), adjusted for co-variates: age and ethnicity.
b. P significant at <.05.