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Dose Adjustments of Ivabradine Based on Resting Heart Rate10
| Heart Rate | Dose Adjustment |
|---|---|
| Greater than 60 bpm | Increase dosage by 2.5 mg twice daily up to a maximum dosage of 7.5 mg twice daily. |
| 50 to 60 bpm | Maintain dosage. |
| Less than 50 bpm or signs and symptoms of bradycardia | Decrease dosage by 2.5 mg twice daily; if current dosage is 2.5 mg twice daily, discontinue therapy. |
bpm = beats per minute
