Table 2.
Neuropsychological characteristics of hippocampal and mPFC participants.
| Group | Patient | WAIS-III FSIQ | WMS-III GMI | BN | TT | COWA | WCST | CFT | BDI | APP | SIP |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Hippocampus | 1606 | 91 | 66 | 32 | 44 | 43 | 6 | 34 | 9 | No | 1 |
| 1846 | 84 | 57 | 43 | 41 | 24 | 6 | 28 | 9 | No | 1 | |
| 1951 | 106 | 57 | 49 | 44 | 40 | 6 | 32 | 5 | No | 2 | |
| 2308 | 98 | 45 | 52 | 44 | 24 | N/A | 26 | 0 | No | 3 | |
| 2363 | 98 | 73 | 58 | 44 | 26 | 6 | 26 | N/A | No | 1 | |
| 2563 | 94 | 63 | 52 | 44 | 36 | 6 | 36 | 0 | No | 1 | |
| Mean (SD) | 95.2 (7.4) | 60.2 (9.6) | 47.7 (9.1) | 43.5 (1.2) | 32.2 (8.5) | 6 (0.0) | 30.3 (4.3) | 4.6 (4.5) | 0.0 (0.0) | 1.5 (0.8) | |
| mPFC | 318 | 143 | 109 | 60 | 44 | 54 | 6 | 36 | 0 | Yes (-3) | 3 |
| 2352 | 106 | 109 | 54 | 44 | 34 | 6 | 32 | 1 | Yes (-3) | 2 | |
| 2391 | 109 | 132 | 57 | 43 | 59 | 6 | 34 | 4 | Yes (-2) | 2 | |
| 2577 | 84 | 96 | 55 | 44 | 44 | 0 | 31 | 7 | Yes (-3) | 3 | |
| 3350 | 118 | 108 | 52 | N/A | 40 | 6 | 36 | 3 | Yes (-1) | 1 | |
| Mean (SD) | 112 (21.4) | 110.8 (13.1) | 55.6 (3.0) | 43.8 (0.5) | 46.2 (10.2) | 4.8 (2.7) | 33.8 (2.3) | 3.0 (2.7) | -2.4 (0.9) | 2.2 (0.8) |
Note. WAIS-III FSIQ = Wechsler Adult Intelligence Scale-III Full Scale Intelligence Quotient; WMS-III = Wechsler Memory Scale-III General Memory Index; BN = Boston Naming Test; TT = Token Test; COWA = Controlled Oral Word Association Test; WCST = Wisconsin Card Sort Test Number of Categories Achieved; CFT = Complex Figure Test Copy; BDI = Beck Depression Inventory; APP = Acquired Personality Problems; SIP = Social Conduct and Interpersonal Functioning; N/A = not available. APP = Acquired Personality Problems refer to whether or not the participant had acquired problems in personality functioning, as derived from data on the Iowa Scales of Personality Change. The numbers in parentheses denote the degree of severity, where 1 = mild, 2 = moderate, and 3 = severe; SIP = The extent of post-lesion change or impairment in aspects of social conduct and interpersonal functioning was rated on a three-point scale, with 1 = no change in impairment, 2 = moderate change or impairment, 3 = severe change or impairment. Characterizations of Acquired Personality Problems and Social and Interpersonal Functioning were rendered by a board-certified clinical neuropsychologist who was blind to the hypothesis of the current study at the time the ratings were performed.