Table 2. Allele frequencies of TrkB gene in PSD and NPSD.
SNP | Allele frequency, N (%) | χ2 | P-value | OR(95%CI) | |
---|---|---|---|---|---|
rs1212171 | C | T | |||
PSD | 275(44.07) | 349(55.93) | 0.679 | 0.410 | 0.918(0.749–1.125) |
NPSD | 436(46.19) | 508(53.81) | |||
rs1778929 | C | T | |||
PSD | 340(54.49) | 284(45.51) | 9.464 | 0.002 | 0.725(0.590–0.890) |
NPSD | 588(62.29) | 356(37.71) | |||
rs1187323 | A | C | |||
PSD | 467(74.84) | 157(25.16) | 16.602 | 0.000 | 0.598(0.466–0.767) |
NPSD | 786(83.47) | 158(16.74) |
TrkB, Tyrosine kinase receptor B; PSD, Post-stroke depression; NPSD, Non post-stroke depression. SNP, Single-nucleotide polymorphism