Table 4. Helper T-cell epitopes of the N protein of MERS-CoV selected on the basis of maximum HLA binding alleles.
Epitope core sequence (9 -mer) | Position | No. of binding HLA-DR alleles | Conservancy (%) | Allergenicity |
---|---|---|---|---|
FNMVQAFGL | 260–268 | 173 | 90 | No |
LRYSGAIKL | 329–337 | 356 | 91 | No |
LQALESGKV | 222–230 | 139 | 89 | No |
LNRLQALES | 219–227 | 144 | 90 | No |
FMGMSQFKL | 306–314 | 100 | 91 | No |
LYLDLLNRL | 214–222 | 160 | 90 | No |
IKQLAPRWY | 91–99 | 154 | 89 | No |
FLRYSGAIK | 328–336 | 142 | 91 | No |
LLYLDLLNR | 213–221 | 110 | 90 | No |
VKQSQPKVI | 230–238 | 94 | 89 | No |