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. 2015 Dec 7;10(12):e0144508. doi: 10.1371/journal.pone.0144508

Fig 11. A model shows how ALPCs affects nuclear import and export in the cytoplasm.

Fig 11

ALPCs may serve as the docking or assembling sites for importin α/β-mediated import complexes followed by their dissociation for nuclear import. On the other hand, the ALPC-associated RanBP2/RanGAP1*SUMO1/Ubc9 complexes may function in the disassembly of CRM1-mediated export complexes by mediating RanGTP hydrolysis.