Table 5. Kaplan-Meier univariate analysis of patients with NSRC.
Variable | n | 5-Year survival rate (%) | P value |
---|---|---|---|
Sex | 0.960 | ||
Male | 941 | 49.2 | |
Female | 385 | 50.1 | |
Age (yr) | <0.001 | ||
<60 | 681 | 54.8 | |
≥60 | 645 | 43.9 | |
Tumor size (cm) | <0.001 | ||
<5 | 818 | 58.4 | |
≥5 | 508 | 35.0 | |
Tumor location | <0.001 | ||
Upper third | 484 | 39 | |
Middle third | 214 | 46.7 | |
Lower third | 565 | 62.5 | |
Two-third or more | 63 | 22.2 | |
Venous tumor emboli | <0.001 | ||
Yes | 471 | 28.0 | |
No | 855 | 61.3 | |
Nervous invasion | <0.001 | ||
Yes | 508 | 29.7 | |
No | 818 | 61.7 | |
Serosa invasion | <0.001 | ||
Yes | 893 | 33.4 | |
No | 433 | 82.7 | |
Lymph node metastasis | <0.001 | ||
Yes | 867 | 32.4 | |
No | 459 | 81.7 | |
TNM stage | <0.001 | ||
Stage I | 311 | 93.2 | |
Stage II | 327 | 58.7 | |
Stage III | 688 | 25.3 | |
P21 expression | 0.173 | ||
Positive | 883 | 47.9 | |
Negative | 443 | 52.6 | |
P53 expression | 0.924 | ||
Positive | 966 | 49.6 | |
Negative | 360 | 49.2 | |
c-myc expression | 0.510 | ||
Positive | 850 | 49.1 | |
Negative | 476 | 50.2 | |
EGFR expression | 0.037 | ||
Positive | 532 | 45.3 | |
Negative | 794 | 52.3 |