Figure 2.

Low-density lipoprotein (LDL) inflammatory index (LII). A, LDL from patients with idiopathic or associated pulmonary arterial hypertension (IPAH or APAH, respectively) was isolated via fast-performance liquid chromatography, and the LII was determined as described in “Methods.” B, To determine the effect of incubation with 4F, LDL samples were treated with either saline (IPAH Sham Rx, APAH Sham Rx) or 4F (IPAH 4F Rx, APAH 4F Rx), and the LII was determined by incubation with cultured aortic endothelial cells. The values for the patient LDL was divided by the value for a standard LDL preparation from a healthy control subject. Values are means ± SD.