Table 2.
Acute cardiac catheterization hemodynamics
| Baseline | After 360 minutes | |||
|---|---|---|---|---|
| Measurement | Ranolazine | Placebo | Ranolazine | Placebo |
| mRAP, mmHg | 2.0 (3.0) | 3.0 (3.5) | 6.5 (3.3) | 8.0 (3.0) |
| PASP, mmHg | 71.5 (30.0) | 59.5 (33.0) | 75.0 (38.5) | 56.5 (39.8) |
| PADP, mmHg | 30.0 (16.5) | 29.0 (16.3) | 31.0 (16.3) | 28.0 (16.0) |
| mPAP, mmHg | 42.5 (23.8) | 36.5 (20.5) | 47.5 (27.8) | 40.0 (24.5) |
| PCWP, mmHg | 11.0 (5.0) | 11.0 (2.0) | … | … |
| CO, L/min2 | 5.9 (1.0) | 4.6 (0.5) | 5.9 (1.0) | 6.2 (1.7) |
| CI, L/min × m2 | 3.1 (0.6) | 2.4 (0.3) | 2.8 (0.7) | 3.2 (0.9) |
| PVR, Wood units | 5.8 (3.7) | 5.9 (3.5) | 7.4 (3.9) | 6.1 (3.6) |
Note
Data are median (IQR). Legend: CI: cardiac index; CO: cardiac output; IQR: interquartile range; mPAP: mean pulmonary artery pressure; mRAP: mean right atrial pressure; PADP: pulmonary artery diastolic pressure; PASP: pulmonary artery systolic pressure; PCWP: pulmonary capillary wedge pressure; PVR: pulmonary vascular resistance.