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Change in 6-minute walk distance (6MWD) and time to clinical worsening (TCW) by sex
| Tadalafil | Placebo | |||
|---|---|---|---|---|
| Sex, parameter | n | Mean (SD) | n | Mean (SD) |
| Male | ||||
| Change in 6MWD, m | 62 | 48.6 (55)a | 14 | 26.4 (63) |
| TCW, days | 8 | 79 (36)b | 3 | 62.3 (13) |
| Female | ||||
| Change in 6MWD, m | 210 | 34.7 (54)a | 54 | 16.5 (52) |
| TCW, days | 21 | 61 (29)b | 10 | 39 (28) |
P = 0.01 for the difference between male and female change in 6MWD.
P = 0.49 for the difference between male and female change in TCW.
