Table 2.

The confounders selected and matched from ten included studies

Placebo				Sulodexide				Difference significance	References
Patients(n)	Mean Age*, y	Initial status of the kidney*	Mean arterial pressure before treatment mmHg	Patients (n)	Mean age*, y	Initial status of the kidney*	Mean arterial pressure before treatment mmHg
18	33.3	109.0±11.8 mL/min#	133.3	18	27.9	122.7±22.7 mL/min	120.6	No	Dedov et al18
56	47.0	5.10 μg/min (log)ǂ	140.9	56	47.4	4.58–5.25 μg/min (log)ǂ	136.1–139.7	No	Gambaro et al22
13	36.8	106.8 mg/d	N/A	30	34.6	126.1 mg/d	N/A	No	Sulikowska et al19
47	60.3	97.8 mg/d	128	50	64.1	124.8–134.1 mg/d	129	No	Heerspink et al21
29	60.3	110.74 μg/min	129	33	59.0	113 μg/min	134.4	No	Kang20
532	62.3	108.4 mg/g§	131.4	524	62.0	107.3 mg/g	130.7	No	Lewis et al11
629	63.6	1,364 mg/g§	138.0	619	62.3	1,415 mg/g	138.0	No	Packham et al12
37	45.5	1.99±0.56 mg/g	125	38	45.5	2.03±0.79 mg/g	125	No	Bu et al51
22	62.8	2.18 g/d	N/A	23	62.8	2.23 g/d	N/A	No	Liu52
30	51.7	590.7 mg/d	N/A	35	50.0	600.2 mg/d	N/A	No	Xiong53

Notes:

^*Data are expressed as the mean value, unless indicated otherwise.

^ǂAER.

^#Creatinine clearance.

^§ACR.

Abbreviations: ACR, albumin/creatinine ratio; AER, albumin excretion rate; N/A, not available; y, years; min, minute; d, day.