Figure 6.

Effects of GBE on the expression of cytoplasmic IκBα and NF-κB by western blotting analysis.

Notes: (A) The Western blotting results of the cytoplasmic IκBα, NF-κB, and β-Tubulin. (B) The data analysis of Western blotting about IκBα and NF-κB. Both (A) and (B) showed that GBE treatment dose-dependently increased the cytoplasmic IκBα and NF-κB levels compared with group M but failed to reach the levels of group C. (C) The purity was assayed by anti-β-Tubulin or anti-Histone H3 antibodies for the cytoplasmic or nuclear compartments, respectively. GBE treatment dose-dependently increased the cytoplasmic IκBα and NF-κB levels compared with group M but failed to reach the levels of group C. The purity was assayed by anti-β-tubulin or anti-histone H3 antibodies for the cytoplasmic or nuclear compartments, respectively.

Abbreviations: C, control group; GBE, Ginkgo biloba extract; H, high-dose group; L, low-dose group; M, model group.