Table 2.
The relationship between the recent curative effect with UGT1A1 different genotypes
| Item | Genotype (n) | Genotype (n) | Genotype (n) | Genotype (n) | P-value |
|---|---|---|---|---|---|
| UGT1A1*28 | UGT1A1*28 | UGT1A1*6 | UGT1A1*6 | ||
| TA6/6 (56) | TA6/7 (11) | G/G (45) | G/A (22) | ||
| CR | 6 (11.6%) | 1 (10.9%) | 4 (9.9%) | 2 (10.2%) | 0.359 |
| PR | 27 (46.8%) | 5 (47.2%) | 22 (48.1%) | 12 (49.0%) | 0.472 |
| SD | 12 (21.9%) | 2 (22.8%) | 9 (20.1%) | 4 (20.4%) | 0.261 |
| PD | 11 (19.7%) | 3 (19.1%) | 10 (20.9%) | 4 (20.4%) | 0.533 |
Abbreviations: CR, complete response; PD, progressive disease; PR, partial response; SD, stable disease; UGT, uridine diphosphate glucuronosyltransferase.