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. 2015 Dec 1;8:3565–3573. doi: 10.2147/OTT.S95395

Figure 6.

Figure 6

Effect of FOXO1 gene knockdown on cell cycle distribution of PTC cells. Cell cycle distribution was analyzed by flow cytometry 48 hours after transfection of PTC cells with FOXO1 siRNA or NC RNA (200 nmol/L).

Notes: (A) The proportion of G0/G1 phase, S-phase, and G2/M phase cells in FOXO1 siRNA and NC groups of TPC1 cells. (B) The proportion of G0/G1 phase, S-phase, and G2/M phase cells in FOXO1 siRNA and NC groups of K1 cells. *P<0.05 (two-tailed t-test).

Abbreviations: FOXO1, forkhead box protein O1; NC, negative control; PTC, papillary thyroid carcinoma; siRNA, small interfering RNA.