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Impact of FAS overexpression on radiation response phenotype in basal cell lines with low levels of baseline FAS. Panel A: FAS overexpressing MDMBA231 and AU565 cell lines treated with CH11 demonstrate induction of the apoptosis proteases, caspases 3, 8 and 9 and c-PARP. Panel B: Reintroduction of FAS signaling enhanced radiation response in both basal cell lines.
