Table 4. Fuhrman grading of renal cell carcinoma (RCC) nuclear.
Fuhrman grade | Nuclear morphology and size | Nucleus morphology |
---|---|---|
Grade I | Round and uniform, sized about 10 μm, with regular nuclear membrane | Absent |
Grade II | Slightly irregular nuclear membrane, with nuclear sized about 15 μm | Inconspicuous (visible at ×40) |
Grade III | Irregular nuclear membrane, with nuclear sized about 20 μm | Conspicuous (visible at ×10) |
Grade IV | Irregular nuclear membrane, pleomorphic, multi-lobed with clumped chromatin; with nuclear sized at least 20 μm | Very prominent |