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. 2015 Nov 9;45(Suppl 1):33–49. doi: 10.1007/s40279-015-0393-9

Table 3.

Effect of up to 28 days of adaptation to high-fat low carbohydrate diet on performance of trained individuals

Athletes LCHF adaptation protocol Performance protocol Nutritional status/strategies for performance Performance advantage with LCHF
Moderately trained cyclists [33] (n = 7 F)
Crossover design
7 days
LCHF (fat = 59 % E, CHO = 1.2 g/kg BM)
HC (CHO = 6.4 g/kg BM)
Cycling
TTE at 80 % VO 2max
3–4 h after meal, no CHO intake during exercise No
In fact, performance deteriorated with LCHF. Time to exhaustion reduced by 47 % on LCHF trial
Well-trained cyclists [34] (n = 5 M)
Crossover design
14 days
LCHF (fat = 67 % E, CHO = 17 % Ea)
HC (CHO = 74 % Ea)
Cycling
30 s Wingate test + TTE at 90 % VO2max + TTE at 60 % VO 2max
Overnight-fasted + no CHO intake during exercise No: two higher intensity tests
Yes: Submaximal cycling
Time to exhaustion increased by 87 % on LCHF trial commenced with lower glycogen stores due to preceding exercise
Well-trained cyclists [35] (n = 16 M)
Parallel-group design
15 days
LCHF (fat = 69 %E, CHO = 2.2 g/kg BM)
HC (CHO = 5.5 g/kg BM)
Cycling
150 min at 70 % VO 2max + 40 km TT
Performance measured at t = 0, 5, 10, and 15 days
MCT intake 1.5 h before event (~14 g)
MCT (0.3 g/kg/h) and CHO (0.8 g/kg/h) during exercise
No
TT performance increased over time in both groups as a result of training protocol. Significant improvements seen in both groups by day 10, but no difference in mean improvement between groups. Important finding of study: adaptations achieved after only 5 days of high-fat diet
Well-trained cyclists [36] (n = 7 M)
Crossover design
14 days
LCHF (fat = 66 % E, CHO = ~2.4 g/kg)
HC (CHO = ~8.6 g/kg, 70 % CHO)
Cycling
5 h including 15 min TT + 100 km TT
LCHF = high-fat pre-event meal
HC = high CHO pre-event meal
Both: 0.8 g/kg/h CHO during ride
Yes: submaximal intensity exercise
No: higher-intensity exercise
Relative to baseline: HC showed small NS decreases in performance of both 15 min TT and 100 km TT
LCHF showed larger but NS decrease in performance of 15 min TT but small NS improvement in 100 km TT
Well-trained duathletes [37] (n = 11 M)
Crossover design
5 weeks
LCHF (fat = 53 % E, CHO = ~3.6 g/kg)
HC (CHO = ~6.9 g/kg, 68 % CHO)
Cycling
40 min incremental protocol + 20 min TT @ ~89 % VO 2max
Running (separate day)
Outdoor 21 km TT
LCHF = high-fat pre-event meal
HC = high CHO pre-event meal
Intake pre and during half marathon not stated
No
Self-selected work output similar for cycling TT in both dietary treatments (298 ± 6 vs. 297 ± 7 W, NS) for LCHF and HC, respectively. Half marathon time not different between trials (80 min 12 s ± 86 s vs. 80 min 24 s ± 82 s, NS)

BM body mass, CHO carbohydrate, E energy F female, HC high-carbohydrate diet, LCHF low-carbohydrate high-fat diet, M male, MCT medium chain triglyceride, NS not significant, TT time trial, TTE time to exhaustion, VO 2 max maximal oxygen uptake

ag/kg intakes unavailable