Table 3.
Comparison of complement proteins identified on the cell surface of C. albicans by shaving after incubation with NS vs. HIS.
| Complement proteins | Normal serum (NS) | Heat inactivated serum (HIS) |
|---|---|---|
| Lectin pathway | 7 proteins | 7 proteins |
| Collectin-11, MASP2, Ficolin-3*, C2*, C3, C4-A, C4-B | MASP2*, Ficolin-2, Ficolin-3, C2*, C3, C4-A, C4-B | |
| Classical pathway | 8 proteins | 10 proteins |
| C1qB, C1qC, C1r, C1s, C2*, C3, C4-A, C4-B | C1qA, C1qB, C1qC, C1r, C1r-like, C1s, C2, C3, C4-A, C4-B | |
| Alternative pathway | 3 proteins | 4 proteins |
| C3, FB, FP | C3, FB, FD, FP* | |
| Membrane attack complex (MAC) | 7 proteins | 7 proteins |
| C5, C6, C7, C8-A, C8-B, C8-G, C9 | C5, C6, C7, C8-A, C8-B, C8-G, C9 | |
| Complement inhibitors | 7 proteins | 9 proteins |
| A2M, C4BPA, C4BPB*, clusterin, FH, FI*, vitronectin | A2M, C1INH, C4BPA, C4BPB, clusterin, FH, FI, GPLD1, vitronectin |
Proteins indicated in bold are only identified in one condition.
Proteins with
*
are identified only in one replicate of the indicated condition.