Table 2.
Odds ratio (OR) and 95% confidence interval (CI) of CAD patients associated with genotyping frequencies of CCL5-403 and CCR5-59029.
| Variable | Non-CAD (n = 161) (%) | CAD (n = 322) (%) | OR (95% CI) | p value |
|---|---|---|---|---|
| CCL5-403 | ||||
| CC | 85 (52.8%) | 148 (46.0%) | 1.00 | |
| CT | 70 (43.5%) | 142 (44.1%) | 1.165 (0.788–1.723) | 0.444 |
| TT | 6 (3.7%) | 32 (9.9%) | 3.063 (1.231–7.624) | 0.012∗ |
| CC | 85 (52.8%) | 148 (46.0%) | 1.00 | |
| CT or TT | 76 (47.2%) | 174 (54.0%) | 1.315 (0.900–1.921) | 0.157 |
| C | 240 (74.5%) | 438 (68.0%) | 1.00 | |
| T | 82 (25.5%) | 206 (32.0%) | 1.377 (1.019–1.859) | 0.037∗ |
| CCR5-59029 | ||||
| GG | 67 (41.6%) | 132 (41.0%) | 1.00 | |
| GA | 71 (44.1%) | 146 (45.3%) | 1.044 (0.694–1.570) | 0.837 |
| AA | 23 (14.3%) | 44 (13.7%) | 0.971 (0.542–1.741) | 0.921 |
| GG | 67 (41.6%) | 132 (41.0%) | 1.00 | |
| GA or AA | 94 (58.4%) | 190 (59.0%) | 1.026 (0.699–1.506) | 0.896 |
| G | 205 (63.7%) | 410 (63.7%) | 1.00 | |
| A | 117 (36.3%) | 134 (36.3%) | 1.000 (0.757–1.321) | 1.000 |
The odds ratio (OR) with their 95% confidence intervals were estimated by logistic regression.
∗Significance p value < 0.05.