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. 2015 Dec 5;386(10010):2257–2274. doi: 10.1016/S0140-6736(15)00195-6

Table 2.

Change in age-standardised rates (per 100 000) of death, YLLs, YLDs, and DALYs for both sexes from 1990 to 2013 for select disorders in England and total DALYs in 2013

Deaths YLLs YLDs DALYs Total burden of DALYs 2013
Cerebrovascular disease −46·2% (−50·65 to −37·93)* −54·9% (−59·01 to −49·67)* 14·2% (7·89 to 20·12)* −49·8% (−54·40 to −44·69)* 535 900 (475 100 to 607 000)
Chronic obstructive pulmonary disease −19·3% (−27·43 to −2·76)* −32·4% (−39·25 to −21·41)* −0·9% (−12·25 to 10·28) −21·9% (−28·42 to −15·25)* 527 200 (448 800 to 620 400)
Alzheimer's disease and other dementias 6·9% (−6·42 to 20·11) −3·4% (−14·31 to 6·87) 0·2% (−11·40 to 10·40) −2·2% (−11·61 to 5·78) 463 400 (412 800 to 514 600)
Diabetes −50·4% (−53·89 to −46·91)* −55·8% (−58·66 to −52·73)* 75·3% (56·88 to 94·11)* 20·1% (5·51 to 34·98)* 360 200 (262 900 to 468 900)
Prostate cancer −16·2% (−44·83 to 0·52) −20·9% (−51·37 to −6·46)* 42·6% (2·52 to 72·19)* −14·2% (−45·70 to 1·21) 138 100 (93 300 to 186 200)
Liver cancer 56·6% (11·83 to 87·65)* 41·0% (6·19 to 66·01)* 72·3% (18·86 to 126·55)* 41·4% (6·34 to 66·45)* 49 400 (37 500 to 57 200)
Cirrhosis of the liver 41·7% (31·71 to 51·08)* 50·8% (40·64 to 61·31)* 26·2% (20·17 to 32·34)* 50·0% (40·15 to 60·25)* 181 000 (169 000 to 192 500)
Drug use disorders 113·5% (6·99 to 143·31)* 107·7% (4·07 to 137·47)* −4·9% (−9·68 to 0·19) 18·2% (−1·56 to 28·47) 201 200 (157 300 to 246 500)

Data are percent change (95% UI). YLLs=years of life lost. YLDs=years lived with disability. DALYs=disability-adjusted life-years.

*

Statistically significant.

Men only.