. 2015 Dec 7;15:557. doi: 10.1186/s12879-015-1291-3

Table 2.

Univariate associations between emergence of and episode of hepatic decompensation and/or HCC and other parameters (n = 275)

Parameter	Category	No. (%) with decompensation	P Bivariate (Log rank test)
Sex	Male	16 (6)
Sex	Female	3 (10)	0.4
Age	< 44 years	6 (5)
Age	≥ 44 years	13 (8)	0.2
Hepatitis B virus surface antigen	Negative	17 (6)
Hepatitis B virus surface antigen	Positive	2 (25)	0.15
HCV genotype	1–4	13 (6)
HCV genotype	2–3	6 (9)	0.4
HCV RNA load (log₁₀ IU/mL)^a	< 6.7	13 (7)
HCV RNA load (log₁₀ IU/mL)^a	≥ 6.7	5 (8)	0.5
Therapy against HCV during follow-up	No therapy or therapy without SVR^b	16 (6)
Therapy against HCV during follow-up	SVR^b	3 (11)	0.6
CD4 cell count (cells/mm³)	< 200	5 (8)
CD4 cell count (cells/mm³)	≥ 200	14 (6)	0.5
Platelet count (/mm³)	< 150.000	16 (9)
Platelet count (/mm³)	≥ 150.000	3 (3)	0.061
APRI^c score	< 1.5	9 (7)
APRI^c score	≥ 1.5	10 (7)	0.9
Child-Turcotte-Pugh class	A	15 (6)
Child-Turcotte-Pugh class	B	4 (15)	0.002
MELD^d score^e	< 14	17 (7)
MELD^d score^e	≥ 14	0 (0)	0.6
Liver stiffness (kPa)	< 21	7 (5)
Liver stiffness (kPa)	≥ 21	12 (9)	0.18
Progression of liver stiffness ≥ 30 % from baseline^f	No	5 (3)
Progression of liver stiffness ≥ 30 % from baseline^f	Yes	10 (13)	0.011

^aAvailable in 254 patients

^bSVR: Sustained virological response

^cAPRI: AST platelet ratio index

^dModel for end-stage liver disease

^eAvailable in 251 patients

^fEvaluable in 247 patients