Table 3.
Multivariate models for the prediction of hepatic decompensation and/or HCC
| Parameter | Multivariate hazard ratio (95 % CI) | P multivariate | |
|---|---|---|---|
| Model 1 | |||
| Age (years)a | 1.11 (1.01–1.16) | 0.028 | |
| Female sex | 3.2 (0.59–17.16) | 0.177 | |
| SVRb during follow-up | 0.46 (0.12–1.81) | 0.266 | |
| Platelet count (/mm3) ≥ 150.000 | 4.01 (0.81–19.85) | 0.089 | |
| Child-Turcotte-Pugh class A | 1.49 (0.18–12.41) | 0.713 | |
| Baseline liver stiffness ≥ 21 kPa | 1.9 (0.59–6.07) | 0.279 | |
| Model 2 | |||
| Age (years)a | 1.06 (0.99–1.13) | 0.053 | |
| Female sex | 2.36 (0.46–12.09) | 0.302 | |
| SVRb during follow-up | 0.26 (0.06–1.14) | 0.075 | |
| Platelet count (/mm3) ≥ 150.000 | 2.99 (0.61–14.77) | 0.178 | |
| Child-Turcotte-Pugh class A | 1.88 (0.23–15.55) | 0.556 | |
| Progression of liver stiffness ≥ 30 % from baseline | 4.63 (1.34–16.02) | 0.015 |
aConsidered as a continuous variable for multivariate analyses
bSVR: Sustained virological response. Model 1 indicates the multivariate model based on baseline liver stiffness. Model 2 indicates the multivariate model based on the progression of liver stiffness