Table 1.
Clinicopathological Variables | CD117 | p-value | CD5 | p-value | CD117/CD5 | p-value | ||||
---|---|---|---|---|---|---|---|---|---|---|
positive | negative | positive | negative | positive | negative | |||||
Mean age at surgery | 63 years | 63 years | 63 years | p = 0.79 | 62 years | 63 years | p = 0.13 | 61 years | 63 years | p = 0.25 |
Patient gender | ||||||||||
Male | 1016 (69.3 %) | 89 | 921 | p = 0.03 | 76 | 910 | p < 0.01 | 14 | 852 | p < 0.01 |
Female | 448 (30.5 %) | 56 | 390 | 57 | 383 | 10 | 356 | |||
Histology | ||||||||||
Adenocarcinoma | 711 (48.5 %) | 97 | 611 | p < 0.01 | 123 | 564 | p < 0.01 | 26 | 685 | p < 0.01 |
Squamous Cell Carcinoma | 586 (40.0 %) | 34 | 548 | 0 | 575 | 0 | 586 | |||
Adenosquamous Carcinoma | 55 (3.8 %) | 5 | 49 | 4 | 50 | 1 | 54 | |||
Large Cell Carcinoma | 71 (4.8 %) | 8 | 63 | 3 | 67 | 1 | 70 | |||
Pleomorphic Carcinoma | 42 (2.9 %) | 1 | 41 | 3 | 38 | 0 | 42 | |||
TNM-Classification | ||||||||||
pT1a | 125 (8.5 %) | 21 | 102 | p = 0.07 | 16 | 103 | p = 0.02 | 4 | 121 | p = 0.10 |
pT1b | 158 (10.8 %) | 19 | 138 | 20 | 135 | 5 | 153 | |||
pT2a | 641 (43.8 %) | 62 | 578 | 64 | 554 | 15 | 626 | |||
pT2b | 245 (16.7 %) | 22 | 221 | 16 | 228 | 2 | 243 | |||
pT3 | 248 (16.9 %) | 17 | 230 | 13 | 230 | 1 | 247 | |||
pT4 | 48 (3.3 %) | 4 | 43 | 4 | 44 | 1 | 47 | |||
pN0 | 755 (51.5 %) | 83 | 667 | p = 0.16 | 80 | 651 | p = 0.03 | 16 | 739 | p = 0.57 |
pN1 | 353 (24.0 %) | 27 | 324 | 15 | 330 | 2 | 351 | |||
pN2 | 351 (23.9 %) | 35 | 315 | 38 | 309 | 10 | 341 | |||
pN3 | 6 (0.4 %) | 0 | 6 | 0 | 4 | 0 | 6 | |||
pM0 | 1426 (97.3 %) | 143 | 1275 | p = 0.42 | 129 | 1261 | p = 0.77 | 27 | 1399 | p = 0.53 |
pM1a | 6 (0.4 %) | 0 | 6 | 2 | 4 | 1 | 5 | |||
pM1b | 33 (2.3 %) | 2 | 31 | 2 | 29 | 0 | 33 | |||
Clinical stage | ||||||||||
I A | 190 (12.9 %) | 25 | 162 | p = 0.32 | 25 | 156 | p = 0.05 | 6 | 184 | p = 0.48 |
IB | 344 (23.5 %) | 32 | 312 | 38 | 293 | 7 | 337 | |||
IIA | 277 (18.9 %) | 28 | 248 | 15 | 259 | 3 | 274 | |||
IIB | 165 (11.3 %) | 18 | 145 | 11 | 152 | 1 | 164 | |||
IIIA | 422 (28.8 %) | 40 | 380 | 39 | 376 | 11 | 411 | |||
IIIB | 29 (1.9 %) | 0 | 29 | 2 | 25 | 0 | 29 | |||
IV | 38 (2.6 %) | 2 | 36 | 3 | 33 | 0 | 38 |