Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Dec 8;7:220. doi: 10.3389/fnagi.2015.00220

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Bridi, Barros, Sampaio, Ferreira, Antunes Soares and Romano-Silva.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Acute caffeine exposure translocates DAF-16 to nucleus. (A,B) Caffeine’s exposition for a short period of time translocates DAF-16 from cytoplasm to nucleus. (A) Representative images of worms from the same experimental group and larval stage and (B) fluorescence quantification of daf-16::gfp animals exposed to 5 mM caffeine during different time points. Black bar and gray bars represent control and 5 mM caffeine exposure, respectively. Data are showed as mean ± SD from six random cells from each worm. *p < 0.05 and ***p < 0.0001, caffeine exposed animals compared to control animals. ^#p < 0.0001 animals exposed to caffeine for 30 min and 1 h compared to 48 h exposed animals. n = 12–17 worms were evaluated in each group.