Table 7.
Sensitivity analysis describing the incremental costs of NIPD for paternal exclusion and NIPD for direct diagnosis compared with the current pathway (invasive testing only) at different levels of test uptake and costs
| Scenario | Incremental costs (paternal exclusion) | Incremental costs (direct diagnosis) |
|---|---|---|
| Base case scenario | £9025 | £26 510 |
| 20% eligible for paternal NIPD | £6077 | |
| 40% eligible for paternal NIPD | £12 154 | |
| 80% Uptake of NIPD | £5341 | £14 720 |
| 100% Uptake of NIPD | £10 252 | £30 440 |
| 30% Uptake of IPD | £11 295 | £41 070 |
| 60% Uptake of IPD | £6056 | £7470 |
| Paternal NIPD test costs £300 | £1971 | |
| Paternal NIPD test costs £800 | £16 078 | |
| Direct NIPD test costs £500 | £2760 | |
| Direct NIPD test costs £1000 | £50 260 |
NIPD, non-invasive prenatal diagnosis; IPD, invasive prenatal diagnosis.