Table 2.

Mean (standard deviation) beta-weights and comparison across groups for the negative association between the time series in the dorsolateral prefrontal cortex (DLPFC) and the activity in the accumbens and amygdala (psychophysiological interaction analysis)

	HC (n = 19)	BD-I (n = 16)	BD-II (n = 19)	F(2,53)
Left
DLPFC–amygdala	0.04 (0.14)	0.06 (0.20)	0.17 (0.15)	3.19a BD-II > BD-I, HC
DLPFC–accumbens	0.07 (0.17)	0.10 (0.42)	0.11 (0.24)	0.11
Right
DLPFC–amygdala	0.04 (0.13)	0.08 (0.19)	0.20 (0.23)	3.40a BD-II > BD-I, HC
DLPFC–accumbens	0.05 (0.13)	0.10 (0.35)	0.09 (0.34)	0.16

BD-I = bipolar I disorder; BD-II = bipolar II disorder; HC = healthy controls.

^ap < 0.05.