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. Author manuscript; available in PMC: 2016 Oct 20.
Published in final edited form as: Immunity. 2015 Oct 20;43(4):715–726. doi: 10.1016/j.immuni.2015.10.005

Figure 3. TRIM62 Interacts with Full-length CARD9, but not CARD9 C-terminal Truncations.

Figure 3

(A) HEK293T cells were transfected with indicated constructs followed by immunoprecipitation of tagged CARD9. (B) WT BMDCs were stimulated with depleted zymosan and stained for endogenous CARD9 and TRIM62. Scale bars, 5 μm. (C) Quantification of results shown in (B). (D) CARD9−/− THP-1 cells were transduced with V5-tagged CARD9 WT or CARD9 Δ11 and stimulated with depleted zymosan. Cells were stained for endogenous TRIM62 and tagged CARD9. (E) Quantification of results shown in (D). See also Figure S3.