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. 2015 Dec 3;10:7275–7290. doi: 10.2147/IJN.S91529

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© 2015 Sun et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Specific IgG, IgG1, IgG2a, and IgG2b in the serum antibodies after the nasal mucosal administration of the nanoemulsion vaccine.

Notes: (A) The IgG titer log₂ value of the nanoemulsion. (B) The serum IgG1 optical density of the nanoemulsion vaccine at 450 nm. (C) The serum IgG2a optical density of the nanoemulsion vaccine at 450 nm. (D) The serum IgG2b optical density of the nanoemulsion vaccine at 450 nm. **P<0.01 is considered as a significant difference; *P<0.05 is considered as a difference.

Abbreviations: Ig, immunoglobulin; PBS, phosphate-buffered saline; BNE, blank nanoemulsion; OD, optical density.