Fig. S9.
Effect of cross-environmental tradeoff level between two alternating environments on the crossing ability of randomly generated landscapes. We consider a landscape over six loci of two alleles each (i.e., on a hypercube of dimension 6 and 64 genotypes). For each tradeoff level (i.e., the fraction of mutations having opposite effects in the two environments), random fitness values for each genotype and each environment are drawn to satisfy the tradeoff level between environments. The crossing ability is determined by computing for each tradeoff level the probability p over n = 1,000 (pairs of) landscapes of containing at least one selectively accessible path from the starting genotype to the final genotype in fluctuating conditions. Error bars represent the binomial error .