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. 2015 Nov 16;112(48):E6691–E6698. doi: 10.1073/pnas.1519807112

Table S1.

Circadian expression of mouse liver genes containing RORE DBS after RF15

Genes Function Circadian expression
Ad libitum feeding (ZT20–4 > ZT12–16) RF15 (ZT12–16 > ZT20–4)
ATF5 Transactivator + +
BAX Apoptosis + +
c-Jun Transactivator + +
CDC25c Cell cycle regulator + +
CDKN1A Cell cycle regulator + +
CDK8 Transcriptional coactivator + +
CHEK1 Regulator of DNA damage signaling + +
CREB1 Transactivator = =
CSNK2A1 Casein kinase2, α1 subunit = =
CSNK1D Casein kinase1, δ subunit = =
CUL5 Ubiquitin ligase = =
CYFIP1 FMR1 interacting protein + +
CYP8B1 Bile acid synthesis + +
DAG1 Structural maintenance + +
DR5 Apoptosis + +
DLAT Member of pyruvate dehydrogenase complex = =
ELOVL3 Fatty acid synthesis + +
FGF18 Osteocyte differentiation = =
GCK Glucose metabolism + +
GCKR Glucose metabolism + +
HSD3B5 Cholesterol metabolism + +
HIC53 Phosphatidic acid phosphatase = =
IGFBP4 IGF1 signaling + +
INSIG2A Regulator of lipogenesis + +
IRF1 Transactivator + +
KLF15 Transactivator + +
LIPC Lipoprotein metabolism + +
LRIG1 Regulator of ERBB signaling = =
MGA Transactivator = =
NOD2 Receptor for inflammosome activation + +
PDK4 Glucose metabolism + +
PEX3 Peroxisomal biogenesis + +
PEX16 Peroxisomal biogenesis + +
POFUT1 Fucosyl transferase + +
RAF1 Regulator of MAPK signaling = =
RAB25 Endocytosis = =
ROCK2 Rho-associated kinase = =
U1 Spliceosome assembly = =
UBE2QL1 Ubiquitin conjugating enzyme = =
WDR5B WD-40 repeat protein, subunit 5B = =

+, genes with circadian variation in the transcript levels; =, represent genes with no circadian variation in the transcript levels.