Fig. S3.
Effects of acute restraint (ARS) and acute forced swim (AFS) stressors in naive mice. ARS, which results in no change in the immobility time at the tail-suspension test [in A, TST, F2,21 = 0.17 (stress)], but in decreased time spent in a light chamber of a light–dark box [in B, LDT, F2,21 = 3.97, P < 0.05 (stress)], decreases mGlu2 mRNA transcripts in hippocampus (C) and has no significant effect in NMDA transcripts (D). Instead, AFS results in no significant change in presynaptic mGlu2 and postsynaptic NMDA transcripts (C and D) and in no significant change at the LDT and TST in naive mice (A and B). [mGlu2, F2,21 = 4.92, P < 0.05 (stress); NMDA, F2,12 = 3.87, P < 0.05 (stress).] Bars represent mean + SEM, and * indicates significant comparisons with corresponding controls, *P < 0.05.