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. 2015 Dec 8;11(12):e1005673. doi: 10.1371/journal.pgen.1005673

Fig 2. HBD3 effect on Interferon-β response to polyI:C is potent and is structure dependent.

Fig 2

(A) BMDM from 3 separate mice were treated for 18hr with pI:C (10μg/ml) in the presence and absence of reducing concentration of hBD3 or (B) modified hBD3-cys:ser as indicated and IFNβ, CXCL10 and TNFα measured by ELISA. Image in B shows BMDM treated with 0.5μg/ml TAMRA-hBD3-cys:ser (10 min) observed by fluorescent microscopy. Scale bar 10μM.