Table 2. Clinical factors associated with long diagnostic delay (≥ 18 months) in Crohn’s disease.
| Univariate analysis (Chi-square test) | Multivariate analysis (Logistic regression analysis) | ||||||
|---|---|---|---|---|---|---|---|
| Diagnostic delay ≥ 18 months (N = 283) | Diagnostic delay < 18 months (N = 978) | P value | OR | 95% CI | P value | ||
| Age at diagnosis (%) | |||||||
| ≥ 40 years | 46 (29.7) | 109 (70.3) | 0.006 | 1.64 | 1.11–2.42 | 0.014 | |
| < 40 years | 178 (20.0) | 714 (80.0) | 1 (reference) | ||||
| Gender | |||||||
| Female | 72 (24.8) | 218 (75.2) | 0.094 | 1.30 | 0.94–1.81 | 0.114 | |
| Male | 152 (20.1) | 605 (79.9) | 1 (reference) | ||||
| Family history of IBD (%) | |||||||
| Yes | 8 (34.8) | 15 (65.2) | 0.113 | 1.99 | 0.82–4.87 | 0.130 | |
| No | 216 (21.1) | 808 (78.9) | 1 (reference) | ||||
| Disease location at diagnosis (%) a | |||||||
| Any ileal involvement | 180 (21.1) | 672 (78.9) | 0.659 | 0.87 | 0.59–1.27 | 0.462 | |
| No involvement of ileum | 44 (22.6) | 151 (77.4) | 1 (reference) | ||||
| Concomitant UGI disease (L4) | |||||||
| Yes | 30 (31.6) | 65 (68.4) | 0.011 | 1.83 | 1.14–2.93 | 0.012 | |
| No | 194 (20.4) | 758 (79.6) | 1 (reference) | ||||
| Disease behavior at diagnosis (%) a | |||||||
| Inflammatory (B1) | 170 (19.9) | 685 (80.1) | 0.004 | 1 (reference) | |||
| Stricturing (B2) | 23 (22.1) | 81 (77.9) | 1.03 | 0.62–1.70 | 0.917 | ||
| Penetrating (B3) | 31 (35.2) | 57 (64.8) | 2.22 | 1.38–3.57 | 0.001 | ||
OR, Odds ratio; CI, confidence interval; IBD, inflammatory bowel disease; UGI, upper gastrointestinal.
aDisease location and behavior were determined according to the Montreal classification.