Table 1.
Characteristics of included patients, hospitalized for exacerbations of Crohn’s disease or ulcerative colitis, receiving intravenous corticosteroids
| Characteristic | Steroids Alone | Steroids + Antibiotics | P-value |
|---|---|---|---|
| Ulcerative Colitis | |||
| Patients, n | 88 | 57 | |
| Mean Age (in years) | 35.0 | 35.6 | 0.87 |
| Female, % | 55.7 | 59.7 | 0.64 |
| Extent, % | 0.45 | ||
| Limited colitis | 46.6 | 36.8 | |
| Pancolitis | 53.4 | 63.2 | |
| Previous Therapy, % | |||
| 5-ASA | 90.9 | 84.2 | 0.22 |
| Biologics | 37.5 | 29.8 | 0.34 |
| Immunomodulators | 45.5 | 36.8 | 0.31 |
| Current Therapy % | |||
| 5-ASA | 54.5 | 49.1 | 0.48 |
| Biologics | 21.6 | 17.5 | 0.56 |
| Immunomodulators | 18.1 | 15.9 | 0.76 |
| Crohn’s Disease | |||
| Patients, n | 78 | 131 | |
| Mean age (in years) | 35.1 | 30.2 | 0.06 |
| Female, % | 43.6 | 56.5 | 0.07 |
| Location, % | 0.61 | ||
| Ileocolic | 51.3 | 55.7 | |
| Ileal | 30.8 | 24.4 | |
| Colonic | 18.0 | 19.9 | |
| Upper GI, % | 12.8 | 9.9 | 0.52 |
| Perianal, % | 28.2 | 24.4 | 0.55 |
| Behavior, % | 0.02 | ||
| Inflammatory | 28.1 | 48.1 | |
| Stricturing | 37.2 | 27.5 | |
| Penetrating | 34.6 | 24.4 | |
| Previous Surgeries, % | 39.7 | 29.8 | 0.14 |
| Previous Therapy, % | |||
| 5-ASA | 75.6 | 69.5 | 0.34 |
| Biologics | 47.4 | 47.3 | 0.99 |
| Immunomodulators | 68.0 | 58.0 | 0.15 |
| Current Therapy % | |||
| 5-ASA | 23.1 | 26.0 | 0.63 |
| Biologics | 28.2 | 26.7 | 0.88 |
| Immunomodulators | 29.5 | 18.3 | 0.07 |